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Ghrelin Receptor (GHS-R1A) Antagonism Suppresses Both Alcohol Consumption and the Alcohol Deprivation Effect in Rats following Long-Term Voluntary Alcohol Consumption

Alcohol dependence is a heterogeneous disorder where several signalling systems play important roles. Recent studies implicate that the gut-brain hormone ghrelin, an orexigenic peptide, is a potential mediator of alcohol related behaviours. Ghrelin increases whereas a ghrelin receptor (GHS-R1A) anta...

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Autors principals: Suchankova, Petra, Steensland, Pia, Fredriksson, Ida, Engel, Jörgen A., Jerlhag, Elisabet
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748070/
https://ncbi.nlm.nih.gov/pubmed/23977009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071284
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