Cardiac Per2 Functions as Novel Link between Fatty Acid Metabolism and Myocardial Inflammation during Ischemia and Reperfusion Injury of the Heart

Disruption of peripheral circadian rhyme pathways dominantly leads to metabolic disorders. Studies on circadian rhythm proteins in the heart indicated a role for Clock or Per2 in cardiac metabolism. In contrast to Clock(−/−), Per2(−/−) mice have larger infarct sizes with deficient lactate production...

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Bibliografiske detaljer
Main Authors: Bonney, Stephanie, Kominsky, Doug, Brodsky, Kelley, Eltzschig, Holger, Walker, Lori, Eckle, Tobias
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748049/
https://ncbi.nlm.nih.gov/pubmed/23977055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071493
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