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The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice
The transcytosis of antigens across the follicle-associated epithelium (FAE) of Peyer's patches by microfold cells (M cells) is important for the induction of efficient immune responses to mucosal antigens. The mucosal immune response is compromised by ageing, but effects on M cells were unknow...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3747980/ https://ncbi.nlm.nih.gov/pubmed/23360902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.141 |
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