Mechanisms of Glucose Lowering of Dipeptidyl Peptidase-4 Inhibitor Sitagliptin When Used Alone or With Metformin in Type 2 Diabetes: A double-tracer study

OBJECTIVE: To assess glucose-lowering mechanisms of sitagliptin (S), metformin (M), and the two combined (M+S). RESEARCH DESIGN AND METHODS: We randomized 16 patients with type 2 diabetes mellitus (T2DM) to four 6-week treatments with placebo (P), M, S, and M+S. After each period, subjects received...

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Autori principali: Solis-Herrera, Carolina, Triplitt, Curtis, Garduno-Garcia, Jose de Jesús, Adams, John, DeFronzo, Ralph A., Cersosimo, Eugenio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2013
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747902/
https://ncbi.nlm.nih.gov/pubmed/23579178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-2072
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