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FOXO3a inhibits TNF-α- and IL-1β-induced astrocyte proliferation: implication for reactive astrogliosis

Reactive astrogliosis is one of the pathological hallmarks of neurodegenerative diseases. Inflammatory cytokines, such as TNF-α and IL-1β, have been shown to mediate the reactive astrogliosis in neurodegenerative diseases; however, the molecular mechanism remains unclear. In this study, we investiga...

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Bibliographische Detailangaben
Hauptverfasser: Cui, Min, Huang, Yunlong, Tian, Changhai, Zhao, Yong, Zheng, Jialin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747776/
https://ncbi.nlm.nih.gov/pubmed/21294163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21134
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