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IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase
Glutaminase 1 is the main enzyme responsible for glutamate production in mammalian cells. The roles of macrophage and microglia glutaminases in brain injury, infection, and inflammation are well documented. However, little is known about the regulation of neuronal glutaminase, despite neurons being...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3747774/ https://ncbi.nlm.nih.gov/pubmed/23578284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12263 |
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