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Old Cryptococcus neoformans Cells Contribute to Virulence in Chronic Cryptococcosis

Does cell age matter in virulence? The emergence of persister cells during chronic infections is critical for persistence of infection, but little is known how this occurs. Here, we demonstrate for the first time that the replicative age of the fungal pathogen Cryptococcus neoformans contributes to...

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Detalhes bibliográficos
Main Authors: Bouklas, Tejas, Pechuan, Ximo, Goldman, David L., Edelman, Batya, Bergman, Aviv, Fries, Bettina C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747583/
https://ncbi.nlm.nih.gov/pubmed/23943761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00455-13
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