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A population-based analysis of clustering identifies a strong genetic contribution to lethal prostate cancer

Background: Prostate cancer is a common and often deadly cancer. Decades of study have yet to identify genes that explain much familial prostate cancer. Traditional linkage analysis of pedigrees has yielded results that are rarely validated. We hypothesize that there are rare segregating variants re...

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Bibliografiske detaljer
Main Authors: Nelson, Quentin, Agarwal, Neeraj, Stephenson, Robert, Cannon-Albright, Lisa A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747326/
https://ncbi.nlm.nih.gov/pubmed/23970893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00152
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