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The Loss of Gnai2 and Gnai3 in B Cells Eliminates B Lymphocyte Compartments and Leads to a Hyper-IgM Like Syndrome

B lymphocytes are compartmentalized within lymphoid organs. The organization of these compartments depends upon signaling initiated by G-protein linked chemoattractant receptors. To address the importance of the G-proteins Gα(i2) and Gα(i3) in chemoattractant signaling we created mice lacking both p...

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Библиографические подробности
Главные авторы: Hwang, Il-Young, Park, Chung, Luong, Thuyvi, Harrison, Kathleen A., Birnbaumer, Lutz, Kehrl, John H.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747273/
https://ncbi.nlm.nih.gov/pubmed/23977324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072596
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