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Acute inflammation primes myeloid effector cells for anti-inflammatory STAT6 signaling

The anti-inflammatory drug high-dose intravenous immunoglobulin, widely used to suppress inflammation, depends on a specific α-2,6-sialylated glycoform of IgG Fc to induce Interleukin 4 (IL-4) and Signal Transducer and Activator of Transcription 6 (STAT6) signaling for its activity. Here we show tha...

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Detalhes bibliográficos
Main Authors: Wermeling, Fredrik, Anthony, Robert M., Brombacher, Frank, Ravetch, Jeffrey V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746917/
https://ncbi.nlm.nih.gov/pubmed/23898202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312525110
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