Defective jejunal and colonic salt absorption and altered Na(+)/H(+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice

We investigated the role of the Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) on intestinal salt and water absorption, brush border membrane (BBM) morphology, and on the NHE3 mRNA expression, protein abundance, and transport activity in the murine intestine. NHERF1-deficient mice displayed reduc...

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Main Authors: Broere, N., Chen, M., Cinar, A., Singh, A. K., Hillesheim, J., Riederer, B., Lünnemann, M., Rottinghaus, I., Krabbenhöft, A., Engelhardt, R., Rausch, B., Weinman, E. J., Donowitz, M., Hubbard, A., Kocher, O., de Jonge, H. R., Hogema, B. M., Seidler, U.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746809/
https://ncbi.nlm.nih.gov/pubmed/18758809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-008-0579-1
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