Prefrontal Hypoactivity Associated with Impaired Inhibition in Stimulant-Dependent Individuals but Evidence for Hyperactivation in their Unaffected Siblings

A neurocognitive endophenotype has been proposed for stimulant dependence, based on behavioral measures of inhibitory response control associated with white matter changes in the frontal cortex. This study investigated the functional neuroimaging correlates of inhibitory response control, as functio...

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Main Authors: Morein-Zamir, Sharon, Simon Jones, P, Bullmore, Edward T, Robbins, Trevor W, Ersche, Karen D
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746700/
https://ncbi.nlm.nih.gov/pubmed/23609131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.90
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