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Social Stress Engages Opioid Regulation of Locus Coeruleus Norepinephrine Neurons and Induces a State of Cellular and Physical Opiate Dependence

Stress is implicated in diverse psychiatric disorders including substance abuse. The locus coeruleus–norepinephrine (LC–NE) system is a major stress response system that is also a point of intersection between stress neuromediators and endogenous opioids and so may be a site at which stress can infl...

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Detalhes bibliográficos
Main Authors: Chaijale, Nayla N, Curtis, Andre L, Wood, Susan K, Zhang, Xiao-Yan, Bhatnagar, Seema, Reyes, Beverly AS, Van Bockstaele, Elisabeth J, Valentino, Rita J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746692/
https://ncbi.nlm.nih.gov/pubmed/23660707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.117
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