Exercise and Sodium Butyrate Transform a Subthreshold Learning Event into Long-Term Memory via a Brain-Derived Neurotrophic factor-Dependent Mechanism

We demonstrate that exercise enables hippocampal-dependent learning in conditions that are normally subthreshold for encoding and memory formation, and depends on hippocampal induction of brain-derived neurotrophic factor (BDNF) as a key mechanism. Using a weak training paradigm in an object locatio...

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Detalhes bibliográficos
Main Authors: Intlekofer, Karlie A, Berchtold, Nicole C, Malvaez, Melissa, Carlos, Anthony J, McQuown, Susan C, Cunningham, Michael J, Wood, Marcelo A, Cotman, Carl W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746687/
https://ncbi.nlm.nih.gov/pubmed/23615664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.104
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