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A Reactive Oxygen Species (ROS)-Responsive Polymer for Safe, Efficient, and Targeted Gene Delivery in Cancer Cells

The high intracellular oxidative stress in a cancer cell is a biologically relevant stimulus for efficient intracellular delivery of therapeutic genes. In this study, reactive oxygen species (ROS)-responsive poly(amino thioketal) (PATK) was synthesized to achieve efficient and safe intracellular gen...

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Detalhes bibliográficos
Main Authors: Shim, Min Suk, Xia, Younan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746021/
https://ncbi.nlm.nih.gov/pubmed/23716349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201209633
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