Online Monitoring Oxidative Products and Metabolites of Nicotine by Free Radicals Generation with Fenton Reaction in Tandem Mass Spectrometry

In general, over 70% absorbed nicotine is metabolized to cotinine and trans-3′-hydroxycotinine by cytochrome oxidase P450, and nicotine is also a major addictive and the psychoactive component in cigarettes. As a xenobiotic metabolism, hydrophobic compounds are usually converted into more hydrophili...

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Bibliografische gegevens
Hoofdauteurs: Liang, Shih-Shin, Shiue, Yow-Ling, Kuo, Chao-Jen, Guo, Su-Er, Liao, Wei-Ting, Tsai, Eing-Mei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745948/
https://ncbi.nlm.nih.gov/pubmed/23983622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/189162
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