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Targeting inflammatory pathways in myocardial infarction
Acute cardiomyocyte necrosis in the infarcted heart generates Damage-Associated Molecular Patterns (DAMPs), activating complement and Toll-Like Receptor (TLR)/Interleukin (IL)-1 signaling, and triggering an intense inflammatory reaction. Infiltrating leukocytes clear the infarct from dead cells, whi...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3745791/ https://ncbi.nlm.nih.gov/pubmed/23772948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eci.12118 |
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