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TLR and BCR signals to B cells differentially programme primary and memory Th1 responses to Salmonella enterica()

Protective Th1 responses to Salmonella enterica do not develop in the absence of B cells. Using chimeric mice, we dissect the early (innate) and late (cognate) contributions of B cells to Th programming. B cell intrinsic MyD88 signaling is required for primary effector Th1 development, while antigen...

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Detalhes bibliográficos
Main Authors: Barr, Tom A., Brown, Sheila, Mastroeni, Pietro, Gray, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745605/
https://ncbi.nlm.nih.gov/pubmed/20675594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001431
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