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CTEN prolongs signaling by EGFR through reducing its ligand-induced degradation
Activation of epidermal growth factor receptor (EGFR) triggers signaling pathways regulating various cellular events that contribute to tissue development and function. Aberrant activation of EGFR contributes to tumor progression as well as therapeutic resistance in cancer patients. CTEN (TNS4) is a...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3745516/ https://ncbi.nlm.nih.gov/pubmed/23774213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4441 |
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