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Synthesis and biological evaluation of novel ferrocenyl curcuminoid derivatives

With the purpose to improve the biological activities of curcumin, eight novel ferrocenyl curcuminoids were synthesized by covalent anchorage of three different ferrocenyl ligands. We evaluated their cytotoxicity on B16 melanoma cells and normal NIH 3T3 cells, their inhibition of tubulin polymerizat...

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Main Authors: Arezki, Anusch, Chabot, Guy, Quentin, Lionel, Scherman, Daniel, Jaouen, Gérard, Brulé, Emilie
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745372/
https://ncbi.nlm.nih.gov/pubmed/23967373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0md00231c
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