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Development and in vivo evaluation of gastroretentive delivery systems for cefuroxime axetil

The purpose of this investigation was to design and develop gastroretentive dosage form for cefuroxime axetil using floating tablet approach with various grades of hydroxypropyl methyl cellulose. Cefuroxime axetil is known to have low bioavailability, short half-life and is absorbed largely from upp...

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Detalhes bibliográficos
Main Authors: Rao, Govikari Koteshwar, Mandapalli, Praveen Kumar, Manthri, Rajendraprasad, Reddy, Veerareddy Prabhakar
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745169/
https://ncbi.nlm.nih.gov/pubmed/23960819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2012.01.003
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