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Tadalafil significantly reduces ischemia reperfusion injury in skin island flaps

INTRODUCTION: Numerous pharmacological agents have been used to enhance the viability of flaps. Ischemia reperfusion (I/R) injury is an unwanted, sometimes devastating complication in reconstructive microsurgery. Tadalafil, a specific inhibitor of phosphodiesterase type 5 is mainly used for erectile...

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Bibliographic Details
Main Authors: Kayiran, Oguz, Cuzdan, Suat S., Uysal, Afsin, Kocer, Ugur
Format: Artigo
Language:Inglês
Published: Medknow Publication & Media Pvt Ltd 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745126/
https://ncbi.nlm.nih.gov/pubmed/23960309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0970-0358.113714
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