Src-kinase inhibitors sensitize human cells of myeloid origin to Toll-like-receptor–induced interleukin 12 synthesis

Src-kinase inhibitors hold great potential as targeted therapy against malignant cells. However, such inhibitors may also affect nonmalignant cells and cause pronounced off-target effects. We investigated the role of the dual kinase inhibitor dasatinib on human myeloid cells. Dasatinib is clinically...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wölfl, Matthias, Schwinn, Stefanie, Yoo, Young-Eun, Reß, Marie L., Braun, Matthias, Chopra, Martin, Schreiber, Susanne C., Ayala, Victor I., Ohlen, Claes, Eyrich, Matthias, Beilhack, Andreas, Schlegel, Paul G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744989/
https://ncbi.nlm.nih.gov/pubmed/23836556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-488072
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados