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Gastroretentive hydrodynamically balanced systems of ofloxacin: In vitro evaluation

Hydrodynamically balanced systems (HBSs) of ofloxacin were prepared using lactose, HPMC K4M, PVP K 30, and liquid paraffin, which may increase the mean residence time in the gastrointestinal tract, and may be able to provide maximum drug at the site of absorption to improve oral bioavailability. All...

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Bibliografische gegevens
Hoofdauteurs: Nayak, Amit Kumar, Das, Biswarup, Maji, Ruma
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744977/
https://ncbi.nlm.nih.gov/pubmed/23960825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2011.11.002
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