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Gastroretentive hydrodynamically balanced systems of ofloxacin: In vitro evaluation

Hydrodynamically balanced systems (HBSs) of ofloxacin were prepared using lactose, HPMC K4M, PVP K 30, and liquid paraffin, which may increase the mean residence time in the gastrointestinal tract, and may be able to provide maximum drug at the site of absorption to improve oral bioavailability. All...

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Detalhes bibliográficos
Main Authors: Nayak, Amit Kumar, Das, Biswarup, Maji, Ruma
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744977/
https://ncbi.nlm.nih.gov/pubmed/23960825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2011.11.002
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