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MATCHCLIP: locate precise breakpoints for copy number variation using CIGAR string by matching soft clipped reads
Copy number variations (CNVs) are associated with many complex diseases. Next generation sequencing data enable one to identify precise CNV breakpoints to better under the underlying molecular mechanisms and to design more efficient assays. Using the CIGAR strings of the reads, we develop a method t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744852/ https://ncbi.nlm.nih.gov/pubmed/23967014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00157 |
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