Cargando...
Quantification of free ligand conformational preferences by NMR and their relationship to the bioactive conformation()
Accurate unbound solution 3D-structures of ligands provide unique opportunities for medicinal chemistry and, in particular, a context to understand binding thermodynamics and kinetics. Previous methods of deriving these 3D-structures have had neither the accuracy nor resolution needed for drug desig...
Gardado en:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier Science
2013
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744816/ https://ncbi.nlm.nih.gov/pubmed/23886813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.06.056 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|