The Impact of Inosine Triphosphatase Variants on Hemoglobin Level and Sustained Virologic Response of Chronic Hepatitis C in Korean

Two variants of the inosine triphosphatase (ITPA: rs1127354, rs7270101) gene cause ITPA deficiency and protect against the hemolytic toxicity of ribavirin. We investigated the clinical significance of ITPA variants in Korean patients treated with pegylated interferon (PEG-IFN) plus ribavirin. Of the...

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Main Authors: Kim, Ju Seung, Ahn, Sung-Min, Jung, Young Kul, Kwon, Oh Sang, Kim, Yun Soo, Choi, Duck Joo, Kim, Ju Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Medical Sciences 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744711/
https://ncbi.nlm.nih.gov/pubmed/23960450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2013.28.8.1213
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