Intron Retention in mRNA Encoding Ancillary Subunit of Insect Voltage-Gated Sodium Channel Modulates Channel Expression, Gating Regulation and Drug Sensitivity

Insect voltage-gated sodium (Na(v)) channels are formed by a well-known pore-forming α-subunit encoded by para-like gene and ancillary subunits related to TipE from the mutation “temperature-induced-paralysis locus E.” The role of these ancillary subunits in the modulation of biophysical and pharmac...

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Bibliografski detalji
Glavni autori: Bourdin, Céline M., Moignot, Bénédicte, Wang, Lingxin, Murillo, Laurence, Juchaux, Marjorie, Quinchard, Sophie, Lapied, Bruno, Guérineau, Nathalie C., Dong, Ke, Legros, Christian
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744522/
https://ncbi.nlm.nih.gov/pubmed/23967047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067290
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