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Enhanced Osteogenesis of Adipose Derived Stem Cells with Noggin Suppression and Delivery of BMP-2

Bone morphogenetic proteins (BMPs) are believed to be the most potent osteoinductive factors. However, BMPs are highly pleiotropic molecules and their supra-physiological high dose requirement leads to adverse side effects and inefficient bone formation. Thus, there is a need to develop alternative...

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Detalhes bibliográficos
Main Authors: Fan, Jiabing, Park, Hyejin, Tan, Steven, Lee, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744499/
https://ncbi.nlm.nih.gov/pubmed/23977305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072474
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