β-Catenin-Independent Activation of TCF1/LEF1 in Human Hematopoietic Tumor Cells through Interaction with ATF2 Transcription Factors

The role of Wnt signaling in embryonic development and stem cell maintenance is well established and aberrations leading to the constitutive up-regulation of this pathway are frequent in several types of human cancers. Upon ligand-mediated activation, Wnt receptors promote the stabilization of β-cat...

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Detalhes bibliográficos
Main Authors: Grumolato, Luca, Liu, Guizhong, Haremaki, Tomomi, Mungamuri, Sathish Kumar, Mong, Phyllus, Akiri, Gal, Lopez-Bergami, Pablo, Arita, Adriana, Anouar, Youssef, Mlodzik, Marek, Ronai, Ze'ev A., Brody, Joshua, Weinstein, Daniel C., Aaronson, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744423/
https://ncbi.nlm.nih.gov/pubmed/23966864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003603
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