Roles of DNA polymerases V and II in SOS-induced error-prone and error-free repair in Escherichia coli

DNA polymerase V, composed of a heterotrimer of the DNA damage-inducible UmuC and UmuD [Formula: see text] proteins, working in conjunction with RecA, single-stranded DNA (ssDNA)-binding protein (SSB), β sliding clamp, and γ clamp loading complex, are responsible for most SOS lesion-targeted mutatio...

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Bibliographic Details
Main Authors: Pham, Phuong, Rangarajan, Savithri, Woodgate, Roger, Goodman, Myron F.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Colloquium Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC37442/
https://ncbi.nlm.nih.gov/pubmed/11459974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111007198
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