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High frequency of the X-chromosome inactivation in young female patients with high-grade glioma

BACKGROUND: Gliomas are common tumors and high-grade ones account for 62% of primary malignant brain tumors. Though current evidence have suggested that inherited risks play a role in glioma susceptibility, it was conveyed that glioma was such a complex disease, and the direct genetic contribution t...

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Autors principals: Li, Gang, Zhang, Zhiguo, Jin, Tianbo, Liang, Hongjuan, Tu, Yanyang, Gong, Li, Chen, Zhongping, Gao, Guodong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744161/
https://ncbi.nlm.nih.gov/pubmed/23782947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-8-101
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