Quantitative Muscle MRI as an Assessment Tool for Monitoring Disease Progression in LGMD2I: A Multicentre Longitudinal Study

BACKGROUND: Outcome measures for clinical trials in neuromuscular diseases are typically based on physical assessments which are dependent on patient effort, combine the effort of different muscle groups, and may not be sensitive to progression over short trial periods in slow-progressing diseases....

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Main Authors: Willis, Tracey A., Hollingsworth, Kieren G., Coombs, Anna, Sveen, Marie-Louise, Andersen, Søren, Stojkovic, Tanya, Eagle, Michelle, Mayhew, Anna, de Sousa, Paulo L., Dewar, Liz, Morrow, Jasper M., Sinclair, Christopher D. J., Thornton, John S., Bushby, Kate, Lochmüller, Hanns, Hanna, Michael G., Hogrel, Jean-Yves, Carlier, Pierre G., Vissing, John, Straub, Volker
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743890/
https://ncbi.nlm.nih.gov/pubmed/23967145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070993
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