Differential Post-Surgical Metastasis and Survival in SCID, NOD-SCID and NOD-SCID-IL-2Rγ(null) Mice with Parental and Subline Variants of Human Breast Cancer: Implications for Host Defense Mechanisms Regulating Metastasis

We compare for the first time, the metastatic aggressiveness of the parental MDA-MB-231 breast cancer cell line and two luciferase-tagged in vivo-derived and selected pro-metastatic variants (LM2-4/luc(+) and 164/8-1B/luc(+)) in SCID, NOD-SCID and NOD-SCID-IL-2Rγ(null) (NSG) mice following orthotopi...

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Detalhes bibliográficos
Main Authors: Milsom, Chloe C., Lee, Christina R., Hackl, Christina, Man, Shan, Kerbel, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743873/
https://ncbi.nlm.nih.gov/pubmed/23967178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071270
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