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Discovery of J Chain in African Lungfish (Protopterus dolloi, Sarcopterygii) Using High Throughput Transcriptome Sequencing: Implications in Mucosal Immunity

J chain is a small polypeptide responsible for immunoglobulin (Ig) polymerization and transport of Igs across mucosal surfaces in higher vertebrates. We identified a J chain in dipnoid fish, the African lungfish (Protopterus dolloi) by high throughput sequencing of the transcriptome. P. dolloi J cha...

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Bibliographic Details
Main Authors: Tacchi, Luca, Larragoite, Erin, Salinas, Irene
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743840/
https://ncbi.nlm.nih.gov/pubmed/23967082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070650
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