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Survival of Primary Human Hepatocytes and Death of Induced Pluripotent Stem Cells in Media Lacking Glucose and Arginine

BACKGROUND: Tumorigenicity is an associated risk for transplantation of hepatocytes differentiated from human induced pluripotent stem (hiPS) cells. Hepatocytes express the enzymes galactokinase and ornithine transcarbamylase (OTC) to aid in their own survival. However, hiPS cells do not express the...

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Autors principals: Tomizawa, Minoru, Shinozaki, Fuminobu, Sugiyama, Takao, Yamamoto, Shigenori, Sueishi, Makoto, Yoshida, Takanobu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743790/
https://ncbi.nlm.nih.gov/pubmed/23967260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071897
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