Survival of Primary Human Hepatocytes and Death of Induced Pluripotent Stem Cells in Media Lacking Glucose and Arginine

BACKGROUND: Tumorigenicity is an associated risk for transplantation of hepatocytes differentiated from human induced pluripotent stem (hiPS) cells. Hepatocytes express the enzymes galactokinase and ornithine transcarbamylase (OTC) to aid in their own survival. However, hiPS cells do not express the...

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Main Authors: Tomizawa, Minoru, Shinozaki, Fuminobu, Sugiyama, Takao, Yamamoto, Shigenori, Sueishi, Makoto, Yoshida, Takanobu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743790/
https://ncbi.nlm.nih.gov/pubmed/23967260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071897
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