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A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen

PURPOSE: Gene expression profiling classifies breast cancer into intrinsic subtypes based on the biology of the underlying disease pathways. We have used material from a prospective randomized trial of tamoxifen versus placebo in premenopausal women with primary breast cancer (NCIC CTG MA.12) to eva...

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Autori principali: Chia, Stephen K., Bramwell, Vivien H., Tu, Dongsheng, Shepherd, Lois E., Jiang, Shan, Vickery, Tammi, Mardis, Elaine, Leung, Samuel, Ung, Karen, Pritchard, Kathleen I., Parker, Joel S., Bernard, Philip S., Perou, Charles M., Ellis, Matthew J., Nielsen, Torsten O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743663/
https://ncbi.nlm.nih.gov/pubmed/22711706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0286
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