Cisplatin-incorporated nanoparticles of poly(acrylic acid-co-methyl methacrylate) copolymer

BACKGROUND: Although cisplatin is extensively used in the clinical field, its intrinsic toxicity limits its clinical use. We investigated nanoparticle formations of poly(acrylic acid-co-methyl methacrylate) (PAA-MMA) incorporating cisplatin and their antitumor activity in vitro and in vivo. METHODS:...

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Hlavní autoři: Lee, Kyung Dong, Jeong, Young-Il, Kim, Da Hye, Lim, Gyun-Taek, Choi, Ki-Choon
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2013
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743654/
https://ncbi.nlm.nih.gov/pubmed/23966778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S48367
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