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The quantal nature of Ca(2+) sparks and in situ operation of the ryanodine receptor array in cardiac cells

Intracellular Ca(2+) release in many types of cells is mediated by ryanodine receptor Ca(2+) release channels (RyRCs) that are assembled into two-dimensional paracrystalline arrays in the endoplasmic/sarcoplasmic reticulum. However, the in situ operating mechanism of the RyRC array is unknown. Here,...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Wang, Shi Qiang, Stern, Michael D., Ríos, Eduardo, Cheng, Heping
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC374355/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15004280/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0306157101
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