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Spontaneous proliferation, a response of naïve CD4 T cells determined by the diversity of the memory cell repertoire

T cell numbers are maintained within narrow ranges in vivo. Introduction of naïve cells into lymphopenic environments results in proliferation and differentiation driven by the recognition of peptide/MHC complexes and by cytokine signaling. This process, often described as homeostatic proliferation,...

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Autors principals: Min, Booki, Foucras, Gilles, Meier-Schellersheim, Martin, Paul, William E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC374337/
https://ncbi.nlm.nih.gov/pubmed/15001705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400606101
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