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Spontaneous proliferation, a response of naïve CD4 T cells determined by the diversity of the memory cell repertoire
T cell numbers are maintained within narrow ranges in vivo. Introduction of naïve cells into lymphopenic environments results in proliferation and differentiation driven by the recognition of peptide/MHC complexes and by cytokine signaling. This process, often described as homeostatic proliferation,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC374337/ https://ncbi.nlm.nih.gov/pubmed/15001705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400606101 |
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