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The predicted 3D structure of the human D2 dopamine receptor and the binding site and binding affinities for agonists and antagonists

Dopamine neurotransmitter and its receptors play a critical role in the cell signaling process responsible for information transfer in neurons functioning in the nervous system. Development of improved therapeutics for such disorders as Parkinson's disease and schizophrenia would be significantly en...

Celý popis

Uloženo v:
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kalani, M. Yashar S., Vaidehi, Nagarajan, Hall, Spencer E., Trabanino, Rene J., Freddolino, Peter L., Kalani, Maziyar A., Floriano, Wely B., Kam, Victor Wai Tak, Goddard, William A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC374327/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14999101/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400100101
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