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Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat (Heterocephalus glaber)

The naked mole-rat (NMR, Heterocephalus glaber) is a long-lived mammal in which spontaneous cancer has not been observed. In order to investigate possible mechanisms for cancer resistance in this species, we studied the properties of skin fibroblasts from the NMR following transduction with oncogene...

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Detalhes bibliográficos
Main Authors: Liang, Sitai, Mele, James, Wu, Yuehong, Buffenstein, Rochelle, Hornsby, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743245/
https://ncbi.nlm.nih.gov/pubmed/20550519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00588.x
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