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AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling

Adenosine monophosphate–activated protein kinase (AMPK) is a metabolic regulator that promotes energy conservation and restoration when cells are exposed to nutrient stress. Given the high metabolic requirement of cancer cells, AMPK activation has been suggested as a potential preventative and thera...

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Bibliographic Details
Main Authors: Fox, Melissa M., Phoenix, Kathryn N., Kopsiaftis, Stavros G., Claffey, Kevin P.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743155/
https://ncbi.nlm.nih.gov/pubmed/23946867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913486346
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