Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime–protein boost HIV-1 vaccine in healthy human volunteers

An optimally effective AIDS vaccine would likely require the induction of both neutralizing antibody and cell-mediated immune responses, which has proven difficult to obtain in previous clinical trials. Here we report on the induction of human immunodeficiency virus type-1 (HIV-1)-specific immune re...

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Hauptverfasser: Wang, Shixia, Kennedy, Jeffrey S., West, Kim, Montefiori, David C., Coley, Scott, Lawrence, John, Shen, Siyuan, Green, Sharone, Rothman, Alan L., Ennis, Francis A., Arthos, James, Pal, Ranajit, Markham, Phillip, Lu, Shan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743087/
https://ncbi.nlm.nih.gov/pubmed/18724414
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