Crohn’s disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly

Ileal lesions in Crohn’s disease (CD) patients are colonized by pathogenic adherent-invasive Escherichia coli (AIEC) able to invade and to replicate within intestinal epithelial cells. Recent genome-wide association studies have highlighted the autophagy pathway as being associated with CD risk. In...

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Hlavní autoři: Lapaquette, Pierre, Glasser, Anne-Lise, Huett, Alan, Xavier, Ramnik J., Darfeuille-Michaud, Arlette
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743084/
https://ncbi.nlm.nih.gov/pubmed/19747213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2009.01381.x
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