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Lack of conventional oxygen-linked proton and anion binding sites does not impair allosteric regulation of oxygen binding in dwarf caiman hemoglobin

In contrast to other vertebrate hemoglobins (Hbs) whose high intrinsic O(2) affinities are reduced by red cell allosteric effectors (mainly protons, CO(2), organic phosphates, and chloride ions), crocodilian Hbs exhibit low sensitivity to organic phosphates and high sensitivity to bicarbonate (HCO(3...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weber, Roy E., Fago, Angela, Malte, Hans, Storz, Jay F., Gorr, Thomas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743003/
https://ncbi.nlm.nih.gov/pubmed/23720132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00014.2013
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