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Links between replication and recombination in Saccharomyces cerevisiae: A hypersensitive requirement for homologous recombination in the absence of Rad27 activity

The RAD27 gene of Saccharomyces cerevisiae encodes a 5′-3′ flap exo/endonuclease, which plays an important role during DNA replication for Okazaki fragment maturation. Genetic studies have shown that RAD27 is not essential for growth, although rad27Δ mutants are temperature sensitive. Moreover, they...

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Autors principals: Debrauwère, Hélène, Loeillet, Sophie, Lin, Waka, Lopes, Judith, Nicolas, Alain
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC37430/
https://ncbi.nlm.nih.gov/pubmed/11459962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121075598
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