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DNA Vaccines: Influenza Virus Challenge of a Th2/Tc2 Immune Response Results in a Th2/Tc1 Response in the Lung
For this study, we used DNA-based immunizations to elicit gamma interferon-producing (Tc1) or interleukin 4 (IL-4)-producing (Tc2) CD8 T cells to the influenza virus nucleoprotein. We examined the response of these cells to an intranasal viral challenge. Both the Tc2- and Tc1-biased responses were p...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC374298/ https://ncbi.nlm.nih.gov/pubmed/15047852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.8.4376-4380.2004 |
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