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Estrogen receptor splice variants as a potential source of false-positive estrogen receptor status in breast cancer diagnostics
It is well established that only estrogen receptor (ER)-positive tumors benefit from hormonal therapies. We hypothesized that a subgroup of breast cancer patients expresses estrogen receptor α (ERα), but fails to respond to hormonal therapy due to the expression of a non-functional receptor. We anal...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer US
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3742961/ https://ncbi.nlm.nih.gov/pubmed/23912957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-013-2648-1 |
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